Human calprotectin affects the redox speciation of iron
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چکیده
منابع مشابه
Human Calprotectin Is an Iron-Sequestering Host-Defense Protein
Human calprotectin (CP) is a metal-chelating antimicrobial protein of the innate immune response. The current working model states that CP sequesters manganese and zinc from pathogens. We report the discovery that CP chelates iron and deprives bacteria of this essential nutrient. Elemental analysis of CP-treated growth medium establishes that CP reduces the concentrations of manganese, iron and...
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Determination of Iron and Its Redox Speciation in Seawater Using Catalytic Cathodic Stripping Voltammetry
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Background: Calprotectin is cytotoxic agent that its anti-tumor effects are governed through suppression of topoisomerase II a key enzyme in apoptosis. In previous studies, cytotoxicity and apoptotic effects of calprotectin are shown on different cancer cell lines, but not human gastric cancer cell lines. In the present study, cytotoxicity and apoptotic effects of calprotectin on human gastric ...
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ژورنال
عنوان ژورنال: Metallomics
سال: 2017
ISSN: 1756-5901,1756-591X
DOI: 10.1039/c7mt00044h